90. Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, *Hioki H. (2023) Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum. Neurosci Res. 190:92-106.
PMID:36574563, doi:10.1016/j.neures.2022.11.008
89. Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, *Hioki H. (2023) Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle. Sci Rep. 13(1):323.
PMID:36609635, doi:10.1038/s41598-022-27372-8
88. Nakamura Y, Yahiro T, Fukushima A, Kataoka N, Hioki H, *Nakamura K. (2022) Prostaglandin EP3 receptor-expressing preoptic neurons bidirectionally control body temperature via tonic GABAergic signaling. Sci Adv. 8(51):eadd5463.
PMID:36563142, doi:10.1126/sciadv.add5463
87. Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, *Hioki H. (2022) Fluorochromized Tyramide-Glucose Oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis. Sci Rep. 12(1):14807.
PMID:36097273, doi:10.1038/s41598-022-19085-9
86. #Yamauchi K, #Furuta T, Okamoto S, Takahashi M, Koike M, *Hioki H. (2022) Protocol for multi-scale light microscopy/electron microscopy neuronal imaging in mouse brain tissue. STAR Protoc. 3(3):101508.
PMID:36035789, doi:10.1016/j.xpro.2022.101508
#These authors contributed equally.
85. Yamauchi K, Okamoto S, Takahashi M, Koike M, Furuta T, *Hioki H. (2022) A Tissue Clearing Method for Neuronal Imaging from Mesoscopic to Microscopic Scales. J Vis Exp.
PMID:35635469, doi:10.3791/63941
84. Zhao Q, Ito T, Soko C, Hori Y, Furuyama T, Hioki H, Konno K, Yamasaki M, Watanabe M, Ohtsuka S, Ono M, Kato N, *Yamamoto R. (2022) Histochemical characterization of the dorsal raphe-periaqueductal grey dopamine transporter neurons projecting to the extended amygdala. eNeuro. 9(3):ENEURO.0121-22.2022.
PMID:35580986, doi:10.1523/ENEURO.0121-22.2022
83. Yoshioka Y, Tachibana Y, Uesaka T, Hioki H, Sato Y, Fukumoto T, Enomoto H. (2022) Uts2b is a microbiota-regulated gene expressed in vagal afferent neurons connected to enteroendocrine cells producing cholecystokinin. Biochem Biophys Res Commun. 608(11):66-72.
PMID:35390674, doi:10.1016/j.bbrc.2022.03.117
82. *Kuramoto E, Tanaka YR, Hioki H, Goto T, Kaneko T. (2022) Local Connections of Pyramidal Neurons to Parvalbumin-Producing Interneurons in Motor-Associated Cortical Areas of Mice. eNeuro. 9(1):ENEURO.0567-20.2021.
PMID:34965927, doi:10.1523/ENEURO.0567-20.2021
81. #Furuta T, #Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, *Hioki H. (2022) Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, ScaleSF. iScience. 25(1):10361.
PMID:35106459, doi:10.1016/j.isci.2021.103601
#These authors contributed equally.
80. *Fujimoto H, Notsu E, Yamamoto R, Ono M, Hioki H, Takahashi M, *Ito T. (2021) Kv4.2-Positive Domains on Dendrites in the Mouse Medial Geniculate Body Receive Ascending Excitatory and Inhibitory Inputs Preferentially from the Inferior Colliculus. Front Neurosci. 15:740378
PMID:34658777, doi:10.3389/fnins.2021.740378
79. Kitamura E, *Koike M, Hirayama T, Sunabori T, Kameda H, Hioki H, Takeda S, Itakura A. (2021) Susceptibility of subregions of prefrontal cortex and corpus callosum to damage by high-dose oxytocin-induced labor in male neonatal mice. PLoS One. 16(8):e0256693.
PMID:34437622, doi:10.1371/journal.pone.0256693
78. Takahashi H, Asahina R, Fujioka M, Matsui TK, Kato S, Mori E, Hioki H, Yamamoto T, Kobayashi K, *Tsuboi A. (2021) Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke. Proc Natl Acad Sci U S A. 118(32):e2018850118.
PMID:34349016, doi:10.1073/pnas.2018850118
77. Okamoto S, Yamauchi K, Sohn J, Takahashi M, Ishida Y, Furuta T, Koike M, Fujiyama F, *Hioki H. (2021) Exclusive labeling of direct and indirect pathway neurons in the mouse neostriatum by an adeno-associated virus vector with Cre/lox system. STAR Protoc. 2(1):100230.
PMID:33364620, doi:10.1016/j.xpro.2020.100230
76. Horie S, Kiyokage E, Hayashi S, Inoue K, Sohn J, Hioki H, Furuta T, *Toida K. (2021) Structural basis for noradrenergic regulation of neural circuits in the mouse olfactory bulb. J Comp Neurol. 529(9):2189-2208.
PMID:33616936, doi:10.1002/cne.25085
75. Okamoto K, Ebina T, Fujii N, Konishi K, Sato Y, Kashima T, Nakano R, Hioki H, Takeuchi H, Yumoto J, Matsuzaki M, *Ikegaya Y. (2021) Tb(3+)-doped fluorescent glass for biology. Sci Adv. 7(2):eabd2529.
PMID:33523970, doi:10.1126/sciadv.abd252
74. Elahi M, Motoi Y, Shimonaka S, Ishida Y, Hioki H, Takanashi M, Ishiguro K, *Imai Y, Hattori N. (2021) High-fat diet-induced activation of SGK1 promotes Alzheimer’s disease-associated tau pathology. Hum Mol Genet. 30(18):1693-1710.
PMID:33890983, doi:10.1093/hmg/ddab115
73. Ota K, Oisi Y, Suzuki T, Ikeda M, Ito Y, Ito T, Uwamori H, Kobayashi K, Kobayashi M, Odagawa M, Matsubara C, Kuroiwa Y, Horikoshi M, Matsushita J, Hioki H, Ohkura M, Nakai J, Oizumi M, Miyawaki A, Aonishi T, Ode T, *Murayama M. (2021) Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas. Neuron. 109(11):1810-1824.
PMID:33878295, doi:10.1016/j.neuron.2021.03.032
72. Chen S, He L, Huang AJY, Boehringer R, Robert V, Wintzer ME, Polygalov D, Weitemier AZ, Tao Y, Gu M, Middleton SJ, Namiki K, Hama H, Therreau L, Chevaleyre V, Hioki H, Miyawaki A, Piskorowski RA, *McHugh TJ. (2020) A hypothalamic novelty signal modulates hippocampal memory. Nature. 586(7828):270-274.
PMID:32999460, doi:10.1038/s41586-020-2771-1
71. Katayama H, Hama H, Nagasawa K, Kurokawa H, Sugiyama M, Ando R, Funata M, Yoshida N, Homma M, Nishimura T, Takahashi M, Ishida Y, Hioki H, Tsujihata Y, *Miyawaki A. (2020) Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration. Cell. 181(5):1176-1187.
PMID:32437660, doi:10.1016/j.cell.2020.04.025
70. Okunomiya T, Hioki H, Nishimura C, Yawata S, Imayoshi I, Kageyama R, Takahashi R, *Watanabe D. (2020) Generation of a MOR-CreER knock-in mouse line to study cells and neural circuits involved in mu opioid receptor signaling. Genesis. 58(1):e23341.
PMID:31651080, doi:10.1002/dvg.23341
69. Okamoto S, Sohn J, Tanaka T, Takahashi M, Ishida Y, Yamauchi K, Koike M, Fujiyama F, *Hioki H. (2020) Overlapping Projections of Neighboring Direct and Indirect Pathway Neostriatal Neurons to Globus Pallidus External Segment. iScience. 23(9):101409.
PMID:32877648, doi:10.1016/j.isci.2020.101409
68. Hwang J, Koike M, *Hioki H. (2019) Reduction of Freezing Behavior by Acupuncture Stimulation at HT7 in Contextual Fear-Conditioned Mice. Juntendo Medical Journal. 65(6):554-560.
doi:10.14789/jmj.2019.65.JMJ19-OA17
67. Shibata KI, Tanaka T, Hioki H, *Furuta T. (2018) Projection Patterns of Corticofugal Neurons Associated with Vibrissa Movement. eNeuro. 5(5):ENEURO.0190-18.2018.
PMID:30406196, doi:10.1523/ENEURO.0190-18.2018
66. *Hioki H, Sohn J, Nakamura H, Okamoto S, Hwang J, Ishida Y, Takahashi M, Kameda H. (2018) Preferential inputs from cholecystokinin-positive neurons to the somatic compartment of parvalbumin-expressing neurons in the mouse primary somatosensory cortex. Brain Res. 1695:18-30.
PMID:29792869, doi:10.1016/j.brainres.2018.05.029
65. Norimoto H, Makino K, Gao M, Shikano Y, Okamoto K, Ishikawa T, Sasaki T, Hioki H, Fujisawa S, *Ikegaya Y. (2018) Hippocampal ripples down-regulate synapses. Science. 359(6383):1524-1527.
PMID:29439023, doi:10.1126/science.aao0702
64. Hirai D, Nakamura KC, Shibata KI, Tanaka T, Hioki H, Kaneko T, *Furuta T. (2018) Shaping somatosensory responses in awake rats: cortical modulation of thalamic neurons. Brain Struct Funct. 223(2):851-872.
PMID:28993883, doi:10.1007/s00429-017-1522-z
63. Ohara S, Onodera M, Simonsen OW, Yoshino R, Hioki H, Iijima T, Tsutsui KI, *Witter MP. (2018) Intrinsic Projections of Layer Vb Neurons to Layers Va, III, and II in the Lateral and Medial Entorhinal Cortex of the Rat. Cell Rep. 24(1):107-116.
PMID:29972772, doi:10.1016/j.celrep.2018.06.014
62. Nakano Y, Karube F, Hirai Y, Kobayashi K, Hioki H, Okamoto S, Kameda H, *Fujiyama F. (2018) Parvalbumin-producing striatal interneurons receive excitatory inputs onto proximal dendrites from the motor thalamus in male mice. J Neurosci Res. 96(7):1186-1207.
PMID:29314192, doi:10.1002/jnr.24214
61. Iwano S, Sugiyama M, Hama H, Watakabe A, Hasegawa N, Kuchimaru T, Tanaka KZ, Takahashi M, Ishida Y, Hata J, Shimozono S, Namiki K, Fukano T, Kiyama M, Okano H, Kizaka-Kondoh S, McHugh TJ, Yamamori T, Hioki H, Maki S, *Miyawaki A. (2018) Single-cell bioluminescence imaging of deep tissue in freely moving animals. Science.359(6378):935-939.
PMID:29472486, doi:10.1126/science.aaq1067
60. Okamoto K, Hitora-Imamura N, Hioki H, *Ikegaya Y. (2018) GABAergic malfunction in the anterior cingulate cortex underlying maternal immune activation-induced social deficits. J Neuroimmunol. 321:92-96.
PMID:29957393, doi:10.1016/j.jneuroim.2018.06.006
59. Safari MS, Mirnajafi-Zadeh J, Hioki H, *Tsumoto T. (2017) Parvalbumin-expressing interneurons can act solo while somatostatin-expressing interneurons act in chorus in most cases on cortical pyramidal cells. Sci Rep. 7(1):12764.
PMID:28986578, doi:10.1038/s41598-017-12958-4
58. *Kuramoto E, Pan S, Furuta T, Tanaka YR, Iwai H, Yamanaka A, Ohno S, Kaneko T, Goto T, *Hioki H. (2017) Individual mediodorsal thalamic neurons project to multiple areas of the rat prefrontal cortex: A single neuron-tracing study using virus vectors. J Comp Neurol. 525(1):166-185.
PMID:27275581, doi:10.1002/cne.24054
57. Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K. (2017) Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb. J Comp Neurol. 525(3):574-591.
PMID:27491021, doi:10.1002/cne.24088
56. *Kuramoto E, Iwai H, Yamanaka A, Ohno S, Seki H, Tanaka YR, Furuta T, Hioki H, *Goto T. (2017) Dorsal and ventral parts of thalamic nucleus submedius project to different areas of rat orbitofrontal cortex: A single neuron-tracing study using virus vectors. J Comp Neurol. 525(18):3821-3839.
PMID:28863230, doi:10.1002/cne.24306
55. Sohn J, Takahashi M, Okamoto S, Ishida Y, Furuta T, *Hioki H. (2017) A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped with the Tet-Off System. PLoS One.12(1):e0169611.
PMID:28060929, doi:10.1371/journal.pone.0169611
54. Takahashi A, Islam MS, Abe H, Okubo K, Akazome Y, Kaneko T, Hioki H, *Oka Y. (2016) Morphological analysis of the early development of telencephalic and diencephalic gonadotropin-releasing hormone neuronal systems in enhanced green fluorescent protein-expressing transgenic medaka lines. J Comp Neurol. 524(4):896-913.
PMID:26287569, doi:10.1002/cne.23883
53. Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, *Hioki H. (2016) Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex. Front Neuroanat. 10:124.
PMID:28066195, doi:10.3389/fnana.2016.00124
52. *Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL. (2015) Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons. J Comp Neurol. 523(15):2277-2296.
PMID:25879870, doi:10.1002/cne.23789
51. Hama H, Hioki H, Namiki K, Hoshida T, Kurokawa H, Ishidate F, Kaneko T, Akagi T, Saito T, Saido T, *Miyawaki A. (2015) ScaleS: an optical clearing palette for biological imaging. Nat Neurosci. 18(10):1518-1529.
PMID:26368944, doi:10.1038/nn.4107
50. Nakamura H, *Hioki H, Furuta T, Kaneko T. (2015) Different cortical projections from three subdivisions of the rat lateral posterior thalamic nucleus: a single-neuron tracing study with viral vectors. Eur J Neurosci. 41(10):1294-1310.
PMID:25832313, doi:10.1111/ejn.12882
49. Ueda S, Niwa M, Hioki H, Sohn J, Kaneko T, Sawa A, *Sakurai T. (2015) Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex. Mol Neuropsychiatry. 1(2):94-104.
PMID:26457295, doi:10.1159/000430095
48. Kuramoto E, Ohno S, Furuta T, Unzai T, Tanaka YR, Hioki H, *Kaneko T. (2015) Ventral medial nucleus neurons send thalamocortical afferents more widely and more preferentially to layer 1 than neurons of the ventral anterior-ventral lateral nuclear complex in the rat. Cereb Cortex. 25(1):221-235.
PMID:23968832, doi:10.1093/cercor/bht216
47. Kumar S, Zimmermann K, Hioki H, Pfeifer A, *Baader SL. (2015) Efficient and graded gene expression in glia and neurons of primary cerebellar cultures transduced by lentiviral vectors. Histochem Cell Biol. 143(1):109-121.
PMID:25156294, doi:10.1007/s00418-014-1260-8
46. Suzuki Y, Kiyokage E, Sohn J, Hioki H, *Toida K. (2015) Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb. J Comp Neurol. 523(2):262-280.
PMID:25234191, doi:10.1002/cne.23680
45. Peirs C, Williams SP, Zhao X, Walsh CE, Gedeon JY, Cagle NE, Goldring AC, Hioki H, Liu Z, Marell PS, *Seal RP. (2015 )Dorsal Horn Circuits for Persistent Mechanical Pain. Neuron. 87(4):797-812.
PMID:26291162, doi:10.1016/j.neuron.2015.07.029
44. Sohn J, Hioki H, Okamoto S, *Kaneko T. (2014) Preprodynorphin-expressing neurons constitute a large subgroup of somatostatin-expressing GABAergic interneurons in the mouse neocortex. J Comp Neurol. 522(7):1506-1526.
PMID:24122731, doi:10.1002/cne.23477
43. Ge SN, Li ZH, Tang J, Ma Y, Hioki H, Zhang T, Lu YC, Zhang FX, Mizuno N, Kaneko T, Liu YY, Lung MS, *Gao GD, *Li JL.(2014) Differential expression of VGLUT1 or VGLUT2 in the trigeminothalamic or trigeminocerebellar projection neurons in the rat. Brain Struct Funct. 219(1):211-229.
PMID:23380804, doi:10.1007/s00429-012-0495-1
42. Ebina T, Sohya K, Imayoshi I, Yin ST, Kimura R, Yanagawa Y, Kameda H, Hioki H, Kaneko T, *Tsumoto T. (2014) 3D clustering of GABAergic neurons enhances inhibitory actions on excitatory neurons in the mouse visual cortex. Cell Rep.9(5):1896-907.
PMID:25464846, doi:10.1016/j.celrep.2014.10.057
41. Kataoka N, Hioki H, Kaneko T, *Nakamura K. (2014) Psychological stress activates a dorsomedial hypothalamus-medullary raphe circuit driving brown adipose tissue thermogenesis and hyperthermia. Cell Metab. 20(2):346-358.
PMID:24981837, doi:10.1016/j.cmet.2014.05.018
40. Mizunuma M, Norimoto H, Tao K, Egawa T, Hanaoka K, Sakaguchi T, Hioki H, Kaneko T, Yamaguchi S, Nagano T, Matsuki N, *Ikegaya Y. (2014) Unbalanced excitability underlies offline reactivation of behaviorally activated neurons. Nat Neurosci. 17(4):503-505.
PMID:24633127, doi:10.1038/nn.3674
39. Toyoda Y, Shinohara R, Thumkeo D, Kamijo H, Nishimaru H, Hioki H, Kaneko T, Ishizaki T, Furuyashiki T, *Narumiya S. (2013) EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination. Genes Cells. 18(10):873-85.
PMID:23890216, doi:10.1111/gtc.12081
38. Hioki H, Okamoto S, Konno M, Kameda H, Sohn J, Kuramoto E, Fujiyama F, *Kaneko T. (2013) Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron. J Neurosci.33(2):544-555.
PMID:23303934, doi:10.1523/JNEUROSCI.2255-12.2013
37. Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, *Inoue H. (2013) Modeling Alzheimer’s disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness.Cell Stem Cell. 12(4):487-496.
PMID:23434393, doi:10.1016/j.stem.2013.01.009
36. Kameda H, Hioki H, Tanaka YH, Tanaka T, Sohn J, Sonomura T, Furuta T, Fujiyama F, *Kaneko T. (2012) Parvalbumin-producing cortical interneurons receive inhibitory inputs on proximal portions and cortical excitatory inputs on distal dendrites. Eur J Neurosci. 35(6):838-854.
PMID:22429243, doi:10.1111/j.1460-9568.2012.08027.x
35. Ohno S, Kuramoto E, Furuta T, Hioki H, Tanaka YR, Fujiyama F, Sonomura T, Uemura M, Sugiyama K, *Kaneko T.(2012) A morphological analysis of thalamocortical axon fibers of rat posterior thalamic nuclei: a single neuron tracing study with viral vectors. Cereb Cortex. 22(12):2840-2857.
PMID:22190433, doi:10.1093/cercor/bhr356
34. Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, *Inoue H. (2012) Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med. 4(145):145ra04.
PMID:22855461, doi:10.1126/scitranslmed.3004052
33. Li Z, Ge S, Zhang F, Zhang T, Mizuno N, Hioki H, Kaneko T, *Gao G, *Li J. (2012) Distribution of gephyrin-immunoreactivity in the trigeminal motor nucleus: an immunohistochemical study in rats. Anat Rec (Hoboken).295(4):641-651.
PMID:22290869, doi:10.1002/ar.22426
32. *Watakabe A, Kato S, Kobayashi K, Takaji M, Nakagami Y, Sadakane O, Ohtsuka M, Hioki H, Kaneko T, Okuno H, Kawashima T, Bito H, Kitamura Y, Yamamori T. (2012) Visualization of cortical projection neurons with retrograde TET-off lentiviral vector. PLoS One. 7(10):e46157.
PMID:23071541, doi:10.1371/journal.pone.0046157
31. Ma Y, *Hioki H, Konno M, Pan S, Nakamura H, Nakamura KC, Furuta T, Li JL, Kaneko T. (2011) Expression of gap junction protein connexin36 in multiple subtypes of GABAergic neurons in adult rat somatosensory cortex. Cereb Cortex. 21(11):2639-2649.
PMID:21467210, doi:10.1093/cercor/bhr051
30. Kuramoto E, Fujiyama F, Nakamura KC, Tanaka Y, Hioki H, *Kaneko T. (2011) Complementary distribution of glutamatergic cerebellar and GABAergic basal ganglia afferents to the rat motor thalamic nuclei. Eur J Neurosci.33(1):95-109.
PMID:21073550, doi:10.1111/j.1460-9568.2010.07481.x
29. Tanaka YR, Tanaka YH, Konno M, Fujiyama F, Sonomura T, Okamoto-Furuta K, Kameda H, Hioki H, Furuta T, Nakamura KC, *Kaneko T. (2011) Local connections of excitatory neurons to corticothalamic neurons in the rat barrel cortex. J Neurosci. 31(50):18223-18236.
PMID:22171028, doi:10.1523/JNEUROSCI.3139-11.2011
28. Yahata N, Asai M, Kitaoka S, Takahashi K, Asaka I, Hioki H, Kaneko T, Maruyama K, Saido TC, Nakahata T, Asada T, Yamanaka S, Iwata N, *Inoue H. (2011) Anti-Abeta drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer’s disease. PLoS One. 6(9):e25788.
PMID:21984949, doi:10.1371/journal.pone.0025788
27. Hioki H, Nakamura H, Ma YF, Konno M, Hayakawa T, Nakamura KC, Fujiyama F, *Kaneko T. (2010) Vesicular glutamate transporter 3-expressing nonserotonergic projection neurons constitute a subregion in the rat midbrain raphe nuclei. J Comp Neurol. 518(5):668-86.
PMID:20034056, doi:10.1002/cne.22237
26. *Ohira K, Furuta T, Hioki H, Nakamura KC, Kuramoto E, Tanaka Y, Funatsu N, Shimizu K, Oishi T, Hayashi M, Miyakawa T, *Kaneko T, Nakamura S. (2010) Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells. Nat Neurosci.13(2):173-179.
PMID:20037576, doi:10.1038/nn.2473
25. Ge SN, Ma YF, Hioki H, Wei YY, Kaneko T, Mizuno N, *Gao GD, *Li JL. (2010) Coexpression of VGLUT1 and VGLUT2 in trigeminothalamic projection neurons in the principal sensory trigeminal nucleus of the rat. J Comp Neurol. 518(15):3149-3168.
PMID:20533365, doi:10.1002/cne.22389
24. Kuramoto E, Furuta T, Nakamura KC, Unzai T, Hioki H, *Kaneko T. (2009) Two types of thalamocortical projections from the motor thalamic nuclei of the rat: a single neuron-tracing study using viral vectors. Cereb Cortex. 19(9):2065-2077.
PMID:19174446, doi:10.1093/cercor/bhn231
23. Fujiyama T, Yamada M, Terao M, Terashima T, Hioki H, Inoue YU, Inoue T, Masuyama N, Obata K, Yanagawa Y, Kawaguchi Y, Nabeshima Y, *Hoshino M. (2009) Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development. 136(12):2049-58.
PMID:19439493, doi:10.1242/dev.033480
22. Matsuda W, Furuta T, Nakamura KC, Hioki H, Fujiyama F, Arai R, *Kaneko T. (2009) Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum. J Neurosci. 29(2):444-453.
PMID:19144844, doi:10.1523/JNEUROSCI.4029-08.2009
21. Hioki H, Kuramoto E, Konno M, Kameda H, Takahashi Y, Nakano T, Nakamura KC, *Kaneko T. (2009) High-level transgene expression in neurons by lentivirus with Tet-Off system. Neurosci Res. 63(2):149-154.
PMID:19028532, doi:10.1016/j.neures.2008.10.010
20. Nakamura KC, Fujiyama F, Furuta T, Hioki H, *Kaneko T. (2009) Afferent islands are larger than mu-opioid receptor patch in striatum of rat pups. Neuroreport. 20(6):584-588.
PMID:19287319, doi:10.1097/WNR.0b013e328329cbf9
19. Koshimizu Y, Wu SX, Unzai T, Hioki H, Sonomura T, Nakamura KC, Fujiyama F, *Kaneko T. (2008) Paucity of enkephalin production in neostriatal striosomal neurons: analysis with preproenkephalin-green fluorescent protein transgenic mice.Eur J Neurosci. 28(10):2053-2064.
PMID:19046386, doi:10.1111/j.1460-9568.2008.06502.x
18. Kameda H, Furuta T, Matsuda W, Ohira K, Nakamura K, Hioki H, *Kaneko T. (2008) Targeting green fluorescent protein to dendritic membrane in central neurons. Neurosci Res. 61(1):79-91.
PMID:18342383, doi:10.1016/j.neures.2008.01.014
17. *Ito T, Hioki H, Nakamura K, Kaneko T, Iino S, Nojyo Y. (2008) Some gamma-motoneurons contain gamma-aminobutyric acid in the rat cervical spinal cord. Brain Res. 1201:78-87.
PMID:18294622, doi:10.1016/j.brainres.2008.01.056
16. Nishino E, Yamada R, Kuba H, Hioki H, Furuta T, Kaneko T, *Ohmori H. (2008) Sound-intensity-dependent compensation for the small interaural time difference cue for sound source localization. J Neurosci. 28(28):7153-7164.
PMID:18614685, doi:10.1523/JNEUROSCI.4398-07.2008
15. *Ito T, Hioki H, Nakamura K, Tanaka Y, Nakade H, Kaneko T, Iino S, Nojyo Y. (2007) Gamma-aminobutyric acid-containing sympathetic preganglionic neurons in rat thoracic spinal cord send their axons to the superior cervical ganglion. J Comp Neurol. 502(1):113-125.
PMID:17335042, doi:10.1002/cne.21309
14. Hioki H, Kameda H, Nakamura H, Okunomiya T, Ohira K, Nakamura K, Kuroda M, Furuta T, *Kaneko T. (2007) Efficient gene transduction of neurons by lentivirus with enhanced neuron-specific promoters. Gene Ther. 14(11):872-882.
PMID:17361216, doi:10.1038/sj.gt.3302924
13. Kuramoto E, Fujiyama F, Unzai T, Nakamura K, Hioki H, Furuta T, Shigemoto R, Ferraguti F, *Kaneko T. (2007) Metabotropic glutamate receptor 4-immunopositive terminals of medium-sized spiny neurons selectively form synapses with cholinergic interneurons in the rat neostriatum. J Comp Neurol. 500(5):908-922.
PMID:17177262, doi:10.1002/cne.21216
12. Nakamura K, Watakabe A, Hioki H, Fujiyama F, Tanaka Y, Yamamori T, *Kaneko T. (2007) Transiently increased colocalization of vesicular glutamate transporters 1 and 2 at single axon terminals during postnatal development of mouse neocortex: a quantitative analysis with correlation coefficient. Eur J Neurosci. 26(11):3054-3067.
PMID:18028110, doi:10.1111/j.1460-9568.2007.05868.x
11. Sonomura T, Nakamura K, Furuta T, Hioki H, Nishi A, Yamanaka A, Uemura M, *Kaneko T. (2007) Expression of D1 but not D2 dopamine receptors in striatal neurons producing neurokinin B in rats. Eur J Neurosci. 26(11):3093-3103.
PMID:18028111, doi:10.1111/j.1460-9568.2007.05923.x
10. Martin-Ibanez R, Jenstad M, Berghuis P, Edwards RH, Hioki H, Kaneko T, Mulder J, Canals JM, Ernfors P, Chaudhry FA, *Harkany T. (2006) Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra. Eur J Neurosci. 23(4):1063-1070.
PMID:16519671, doi:10.1111/j.1460-9568.2006.04601.x
9. Nakamura K, Hioki H, Fujiyama F, *Kaneko T. (2005) Postnatal changes of vesicular glutamate transporter (VGluT)1 and VGluT2 immunoreactivities and their colocalization in the mouse forebrain. J Comp Neurol. 492(3):263-288.
PMID:16217795, doi:10.1002/cne.20705
8. Hioki H, Fujiyama F, Nakamura K, Wu SX, Matsuda W, *Kaneko T. (2004) Chemically specific circuit composed of vesicular glutamate transporter 3- and preprotachykinin B-producing interneurons in the rat neocortex. Cereb Cortex.14(11):1266-1275.
PMID:15142960, doi:10.1093/cercor/bhh088
7. Nakamura K, Wu SX, Fujiyama F, Okamoto K, Hioki H, *Kaneko T. (2004) Independent inputs by VGLUT2- and VGLUT3-positive glutamatergic terminals onto rat sympathetic preganglionic neurons. Neuroreport. 15(3):431-436.
PMID:15094498, doi:10.1097/00001756-200403010-00010
6. Wu SX, Koshimizu Y, Feng YP, Okamoto K, Fujiyama F, Hioki H, Li YQ, Kaneko T, *Mizuno N. (2004) Vesicular glutamate transporter immunoreactivity in the central and peripheral endings of muscle-spindle afferents. Brain Res. 1011(2):247-251.
PMID:15157812, doi:10.1016/j.brainres.2004.03.047
5. *Nakamura K, Matsumura K, Hubschle T, Nakamura Y, Hioki H, Fujiyama F, Boldogkoi Z, Konig M, Thiel HJ, Gerstberger R, Kobayashi S, Kaneko T. (2004) Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions. J Neurosci. 24(23):5370-5380.
PMID:15190110, doi:10.1523/JNEUROSCI.1219-04.2004
4. Fujiyama F, Kuramoto E, Okamoto K, Hioki H, Furuta T, Zhou L, Nomura S, *Kaneko T. (2004) Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals. Eur J Neurosci. 20(12):3322-3330.
PMID:15610164, doi:10.1111/j.1460-9568.2004.03807.x
3. Fujiyama F, Hioki H, Tomioka R, Taki K, Tamamaki N, Nomura S, Okamoto K, *Kaneko T. (2003) Changes of immunocytochemical localization of vesicular glutamate transporters in the rat visual system after the retinofugal denervation. J Comp Neurol. 465(2):234-249.
PMID:12949784, doi:10.1002/cne.10848
2. Hioki H, Fujiyama F, Taki K, Tomioka R, Furuta T, Tamamaki N, *Kaneko T. (2003) Differential distribution of vesicular glutamate transporters in the rat cerebellar cortex. Neuroscience. 117(1):1-6.
PMID:12605886, doi:10.1016/s0306-4522(02)00943-0
1. *Kaneko T, Fujiyama F, Hioki H. (2002) Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain. J Comp Neurol. 444(1):39-62.
PMID:11835181, doi:10.1002/cne.10129
11. Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, *Hioki H. (2022) FT-GO: a multiplex fluorescent tyramide signal amplification system for histochemical analysis. bioRxiv
doi:10.1101/2022.07.22.501050
10. Nakamura Y, Yahiro T, Kataoka N, Hioki H, *Nakamura K. (2022) Prostaglandin EP3 receptor-expressing preoptic neurons bidirectionally control body temperature via tonic GABAergic signaling. bioRxiv
doi:10.1101/2022.04.15.488488
9. Yamauchi K, Takahashi M, *Hioki H. (2021) Application of a tissue clearing method for the analysis of dopaminergic axonal projections. In: Experimental Models of Parkinson’s Disease: Methods in Molecular Biology (Ed: Y. Imai), Springer, 2322:141-150.
PMID:34043200, doi:10.1007/978-1-0716-1495-2_14
8. Takahashi M, Ishida Y, Kataoka N, Nakamura K, *Hioki H. (2021) Efficient Labeling of Neurons and Identification of Postsynaptic Sites Using Adeno-Associated Virus Vector. Chapter 22 In: Lujan R., Ciruela F. (eds) Receptor and Ion Channel Detection in the Brain (2nd Ed). Neuromethods, vol 169. pp 323-341, Humana, New York, NY.
doi:10.1007/978-1-0716-1522-5_22
7. *Furuta T, Okamoto-Furuta K, Hioki H. (2021) Analysis of synaptic connections at the electron microscopic level using viral vectors. Chapter 23 In: Lujan R., Ciruela F. (eds) Receptor and Ion Channel Detection in the Brain (2nd Ed). Neuromethods, vol 169. pp 343-352, Humana, New York, NY.
doi:10.1007/978-1-0716-1522-5_23
6. *Hioki H, Nakamura H, Furuta T. (2021) Application of virus vectors for anterograde tract-tracing and single-neuron labeling studies. Chapter 21 In: Lujan R., Ciruela F. (eds) Receptor and Ion Channel Detection in the Brain (2nd Ed). Neuromethods, vol 169. pp 303-322, Humana, New York, NY.
doi:10.1007/978-1-0716-1522-5_21
5. Furuta T#, Yamauchi K#, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, *Hioki H. (2021) Multi-Scale LM/EM Neuronal Imaging from Brain to Synapse with a Tissue Clearing Method, ScaleSF. bioRxiv
doi:10.1101/2021.04.02.438164
4. *Furuta T, Okamoto-Furuta K, Hioki H. (2016) Analysis of synaptic connections using viral vectors at the electron microscopic level. Chapter 19 in Receptors and Ion Channel Detection in the Brain – Methods and Protocols (Neuromethods) edited by Rafael Luján and Francisco Ciruela, Springer, New York, pp.267-275.
doi:10.1007/978-1-4939-3064-7_19
3. *Hioki H, Nakamura H, Furuta T. (2016) Application of virus vectors for anterograde tract-tracing and single-neuron labeling studies. Chapter 18 in Receptors and Ion Channel Detection in the Brain – Methods and Protocols (Neuromethods) edited by Rafael Luján and Francisco Ciruela, Springer, New York, pp.247-266.
doi:10.1007/978-1-4939-3064-7_18
2. Hama H, Hioki H, Namiki K, Hoshida T, Kurokawa H, *Miyawaki A. (2016) Deep imaging of cleared brain by confocal laser-scanning microscopy. Protocol Exchange,
doi:10.1038/protex.2016.019
1. [Review Article] *Hioki H. (2015) Compartmental organization of synaptic inputs to parvalbumin-expressing GABAergic neurons in mouse primary somatosensory cortex. Anat Sci Int, 90:7-21, 2015.
PMID:25467527, doi:10.1007/s12565-014-0264-8